Abstract: The hualage efficiency and economic feasibility constrain the large-scale application of autonomous trucks in open-pit mines in China. Efficient real-time dispatch is a key technology to facilitate the promotion of autonomous driving technology. To address the issue of high-frequency truck dispatch negatively affecting the efficiency of multi-arterial transportation systems in open-pit coal mines, a fixed interval control based real-time truck dispatch strategy (FC strategy) is proposed. The strategy adopts a globally coordinated dispatch mode triggered actively by the dispatch system, monitoring real-time flow-rate at fixed time intervals, predicting whether the production capacity of different hualage routes meets planned demand, and assessing the status of all shovels regarding rich or lack trucks. A truck allocation plan is created based on the number of dispatch, and a capacity loss model is established to evaluate the rationality of truck allocation. The objective is to reduce unnecessary dispatch, minimize the productivity loss caused by frequent dispatch, and improve the production efficiency of the shovel-autonomous truck process in multi-arterial hualage systems. Based on the production data from the Yimin open-pit coal mine, a multi-agent discrete-event simulation system was built for conducting random tests. The results show that, in 50 random trials, the proposed strategy significantly outperforms the DISPATCH strategy in terms of production capacity under multi-arterial hualage systems. Compared to the fixed truck allocation strategy, the proposed strategy improves total production capacity or enhances the path production design completion with a probability of 78%, demonstrating its robustness under unstable production conditions. An analysis of the simulation results with a random seed of 1 shows that, compared to the DISPATCH strategy, the FC strategy has a lower dispatch frequency, with real-time flow-rate fluctuating less around the planned flow-rate, exhibiting higher dispatch accuracy. This indicates that the FC strategy is theoretically applicable to multi-arterial haulage systems in near-horizontal open-pit coal mines and lays a theoretical foundation for the large-scale promotion of autonomous driving technology and future automated dispatch.